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Nonetheless, some individuals who develop despair have no known household historical past of despair, and a few individuals with a identified genetic predisposition to melancholy do not develop the disorder themselves. Thus it is clear that neither genetics nor the setting is solely chargeable for the development of despair. Both may be able to cause depression in an individual within the absence of the opposite, and each could combine to trigger despair. This essay will look at how individuals can develop depression through genetic influences, environmental influences, or a combination of the 2.